Today, there are only a couple of good options for true 4x4 cargo vans: 1) the Mercedes Sprinter 4x4 is the most popular of these...and also the most expensive and hard to get; and 2) Quigley, an aftermarket 4x4 company, will convert just about any cargo van to a true 4x4 version. In 2019, Ford also announced that its popular Ford Transit cargo vans would be available in an all-wheel-drive option.
Now, whether you really need a 4x4 is perhaps a better question. If you live in an area where you regularly utilize 4x4 or AWD just to get around, then a 4x4 or AWD van is probably worth it. However, if you think you need 4x4 because you’re going to be doing a lot of camping or driving to ski resorts, you might instead consider the Ram Promaster, which is the only cargo van that comes with standard front-wheel-drive, which puts all of the weight directly over the front wheels, giving you way more traction than other 2WD vans. We have many clients who own Ram Promasters and regularly take them to the snow and dirt trails (not truly off-roading) without issue.